306- Weight Beyond Calories with Evan Nadler

Dr. Nadler explains why the calories in/calories out approach to weight loss is fundamentally flawed and how our bodies actively resist weight loss through metabolic adaptation. He shares insights from his 20+ years as a pediatric surgeon performing bariatric surgery on children.

• Diets typically result in only 5-7% body weight loss even with intensive effort
• Human bodies evolved to retain weight as a survival mechanism, not lose it
• Genetics plays a major role in obesity, explaining why weight issues run in families
• Epigenetics shows how environmental factors can modify genes across generations
• GLP-1 medications like Ozempic work because they address biological mechanisms
• Mental health and obesity have a bi-directional relationship, each worsening the other
• Getting healthier before having children improves outcomes for the next generation
• Food accessibility and affordability are crucial factors in obesity prevention
• Effective obesity management requires personalized approaches beyond simple diet advice

Listen to the full podcast episode here. You can also watch the full episode below.