The Science of Obesity: Understanding Childhood Obesity with Dr. Evan Nadler (Part 1) | Life in the Bari Lane
In this conversation, Sacha and I dig into what obesity actually is from a medical standpoint. Obesity is a chronic disease, not a personal failure or a simple matter of willpower. Kids don’t “eat their way” into type 2 diabetes. There’s far more going on biologically.
We talk through the role of genetics, epigenetics, trauma, and the brain’s hypothalamic set point, factors that shape a child’s weight long before most people realize. My goal is straightforward: help people understand the science so they can make sense of their own experiences and get the care they deserve.
If you’ve ever wondered why your body seems to fight your progress—or felt shame for what biology predetermined, this episode will change how you see yourself and your story.
In This Episode
What makes childhood obesity different from adult-onset obesity
Why kids can’t “eat themselves” into type 2 diabetes
The role of genetics and epigenetics in shaping weight
How trauma and environment alter gene expression
What the hypothalamic set point really is—and why the body defends it
Key Takeaways
Childhood obesity is a biologically distinct, more aggressive disease.
Diet and exercise alone rarely overcome genetic and epigenetic drivers.
Fat cells develop “memory” that resists long-term weight loss.
Trauma, environment, and even pollution can change gene expression.
Treating obesity early isn’t extreme—it’s evidence-based compassion.
Content Note
Includes discussion of childhood obesity, diabetes, trauma, genetics, and medical interventions such as bariatric surgery and GLP-1 medications. Please listen with care and consult your healthcare provider for personalized guidance.
Listen to the full episode below.
