Doctors flag ‘Ozempic personality’ as some GLP-1 patients lose appetite for life

The injectable drug Ozempic, by Novo Nordisk, is shown on Saturday, July 1, 2023, in Houston. (AP Photo/David J. Phillip, File)more >

In this discussion on what’s being called the “Ozempic personality,” I emphasize that while GLP-1 medications are highly effective at reducing appetite, they can also influence how patients experience reward and pleasure. These drugs don’t just quiet food cravings, they may also dampen other drives, including interest in socializing or everyday activities.

From a clinical standpoint, it’s important to recognize that these effects are not simply side notes, they’re part of how these medications work in the brain. My role is to help patients navigate that balance: achieving meaningful weight loss and metabolic health while maintaining quality of life. With the right monitoring and adjustments, we can individualize treatment so patients feel healthier, not disconnected from the things that matter to them.

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